A student looked at two kinds of cells under a light microscope. One sample was scraped gently from the inside of her cheek. The other was a thin leaf from a pond plant. She drew one cell from each sample, labeled the structures she could see, and named the drawings Cell X and Cell Y. Later she realized she had forgotten to write down which drawing came from which sample.
Her teacher reminded her that all plant and animal cells share some structures, such as a cell membrane, cytoplasm, a nucleus and mitochondria. Other structures are found only in certain kinds of cells, so they can be used as clues.
Which statement correctly identifies Cell Y and gives evidence from the diagram that supports it?
Hint
Look for structures that appear in only one of the two drawings. Structures found in both cells cannot tell them apart.
Step-by-step solution
Where the answer comes from: the passage says all plant and animal cells share "a cell membrane, cytoplasm, a nucleus and mitochondria," so those structures cannot tell the cells apart. The diagram shows that only Cell Y has a cell wall (the thick outer border) and chloroplasts (the green ovals). Cell X has neither.
Step by step:
List what both cells have: cell membrane, cytoplasm, nucleus, mitochondria. These are useless as clues.
List what only Cell Y has: cell wall, chloroplasts, one large central vacuole.
Cell walls and chloroplasts are found in plant cells, not animal cells. So Cell Y is the leaf cell, and Cell X is the cheek cell.
Answer: Cell Y came from the leaf, because it has a cell wall and chloroplasts.
Tip: when a question asks for evidence, the evidence must actually distinguish the choices. A true fact that applies to both cells (both have a nucleus) is not evidence.
Question 2 of 36
Hot spotTwo Cells Under the Microscope
A student looked at two kinds of cells under a light microscope. One sample was scraped gently from the inside of her cheek. The other was a thin leaf from a pond plant. She drew one cell from each sample, labeled the structures she could see, and named the drawings Cell X and Cell Y. Later she realized she had forgotten to write down which drawing came from which sample.
Her teacher reminded her that all plant and animal cells share some structures, such as a cell membrane, cytoplasm, a nucleus and mitochondria. Other structures are found only in certain kinds of cells, so they can be used as clues.
Click on a structure in Cell Y where the energy of sunlight is captured and used to make sugar.
Click on the figure to mark your answer (or focus it and use the arrow keys).
Hint
The process that uses light energy to make sugar is photosynthesis. Which organelle carries it out, and which cell in the diagram has it?
Step-by-step solution
Where the answer comes from: the diagram labels two green ovals in Cell Y as chloroplasts. Chloroplasts are the organelles where photosynthesis happens: they capture light energy and use it to build sugar from carbon dioxide and water.
Step by step:
Translate the question: "captures sunlight and makes sugar" = photosynthesis.
Recall the organelle: photosynthesis takes place in chloroplasts.
Find it in Cell Y: the green ovals, one below the nucleus at the lower left and one at the bottom center. Either one is correct.
Avoid the traps: the mitochondrion releases energy from sugar (cellular respiration), the opposite job; the nucleus holds DNA; the vacuole stores water and dissolved materials.
Answer: click either chloroplast in Cell Y.
Tip: pair the two energy organelles: chloroplasts store light energy in sugar; mitochondria release that energy from sugar as ATP.
Question 3 of 36
Drag and drop
Drag the terms into the boxes to show the levels of organization in the human body, from smallest to largest. Two terms are not used.
Smallest
Largest
Cell
Organism
Tap a tile, then tap a box to place it.
Hint
Each level is made of many units of the level before it. What do you call a group of similar cells working together?
Step-by-step solution
The levels of organization: many similar cells working together form a tissue (for example, cardiac muscle tissue). Several kinds of tissue working together form an organ (the heart contains muscle, nerve and connective tissue). Organs that work together form an organ system (the heart, blood vessels and blood make up the circulatory system). All the organ systems together make up the organism (the whole person).
Step by step:
Start at cell. The next step up is a group of similar cells: tissue.
Tissues combine into an organ.
Organs combine into an organ system.
Organ systems together form the organism, which is already filled in.
Unused terms: an organelle (such as a mitochondrion) is smaller than a cell, so it cannot come after "cell." A population is a group of organisms of the same species, so it is larger than an organism.
Answer: Tissue → Organ → Organ system.
Tip: remember "Cells Tie Organs Onto Systems" or simply: cell, tissue, organ, organ system, organism. Each level is built from the one before it.
Question 4 of 36
Four Mystery Samples
A lab technician examined cells from four unlabeled samples with a powerful microscope. She knows that one sample is a bacterium, one is from an animal, one is from the leaf of a green plant, and one is from a mushroom (a fungus). Fungus cells have a nucleus and a cell wall but no chloroplasts. She recorded which structures she saw and the typical width of the cells.
Structure
Sample 1
Sample 2
Sample 3
Sample 4
Cell membrane
Yes
Yes
Yes
Yes
Ribosomes
Yes
Yes
Yes
Yes
Nucleus
No
Yes
Yes
Yes
Mitochondria
No
Yes
Yes
Yes
Cell wall
Yes
Yes
Yes
No
Chloroplasts
No
No
Yes
No
Typical width (micrometers)
2
8
40
20
Which sample is most likely the bacterium, and what evidence in the table supports this?
Hint
Bacteria are prokaryotes. Which structure do prokaryotic cells lack that all the other cells have?
Step-by-step solution
Where the answer comes from: in the table, Sample 1 is the only sample with "No" in the Nucleus row (and also "No" for mitochondria). It is also the smallest, about 2 micrometers wide.
Step by step:
Bacteria are prokaryotes: their DNA floats in the cytoplasm instead of sitting inside a nucleus, and they have no membrane-covered organelles such as mitochondria.
Scan the Nucleus row: Samples 2, 3 and 4 have one; Sample 1 does not.
Samples 2, 3 and 4 are therefore eukaryotes (fungus, plant and animal).
Answer: Sample 1, because it has no nucleus.
Check: bacteria are usually only a few micrometers long, and Sample 1 is the smallest cell (2 micrometers), which fits.
Tip: good evidence must belong to only one choice. A cell wall or a missing chloroplast is shared by several samples, so it cannot single one out.
Question 5 of 36
The inner lining of the stomach is a thin layer made of many similar cells that work together to release digestive juices. At which level of organization is this layer best classified?
Hint
A group of similar cells doing one job together has a special name. It is one step above a single cell.
Step-by-step solution
Where the answer comes from: the stem describes "many similar cells that work together" to do one job (releasing digestive juices). That is the definition of a tissue.
Step by step:
Recall the levels: organelle → cell → tissue → organ → organ system → organism.
A tissue is a group of similar cells that perform the same function.
The whole stomach is an organ because it is built from several tissues (lining, muscle, nerve and connective tissue).
The stomach, intestines, liver and other organs together form the digestive system, an organ system.
Answer: a tissue.
Check: the layer is made of similar cells doing one job, so it cannot be an organ, which needs several tissue types.
Tip: ask "How many kinds of cells are involved?" One kind working together = tissue; several tissues = organ; several organs = organ system.
Question 6 of 36
Potato Cores in Salt Water
A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.
Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.
Salt concentration (%)
Starting mass (g)
Mass after 24 hours (g)
Change in mass (%)
0 (distilled water)
5.00
5.60
+12
1
4.00
4.12
+3
2
5.00
4.80
−4
4
4.00
3.56
−11
6
5.00
4.20
−16
Which statement best explains why the potato core in distilled water gained mass?
Hint
Distilled water has no dissolved salt. Which side of the cell membrane has more dissolved particles: the water or the inside of the potato cells?
Step-by-step solution
Where the answer comes from: the passage defines osmosis: "water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water)." It also says "Salt does not easily cross the membrane of a potato cell." The table shows the core in distilled water went from 5.00 g to 5.60 g (+12%).
Step by step:
Distilled water has no dissolved particles at all.
Potato cells contain dissolved sugars, salts and other substances, so the inside of the cells has more dissolved particles.
Water therefore moves into the cells by osmosis, and the core gets heavier.
Nothing in distilled water could enter except water, so the extra mass must be water.
Answer: Water moved into the potato cells, where there were more dissolved particles than in the distilled water.
Check: in the 6% salt cup the outside has more dissolved particles, and the core lost mass (−16%), the opposite direction, which fits the same rule.
Tip: in osmosis, follow the water, not the salt: water moves toward the side that is "saltier" (more dissolved particles).
Question 7 of 36
Fill inChromosome Numbers in Different Species
Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.
Organism
Chromosomes in a body cell (2n)
Fruit fly
8
Corn
20
Cat
38
Human
46
Chimpanzee
48
Potato
48
Dog
78
Based on the table, how many chromosomes are in a sperm cell of a dog?
chromosomes
Type your answer in the box. Fractions like 3/4 are fine.
Hint
A sperm cell is a gamete. The passage tells you how a gamete's chromosome number compares with 2n.
Step-by-step solution
Where the answer comes from: the table lists the dog with 78 chromosomes in a body cell (2n). The passage says gametes "are made by meiosis and have half that number (n)."
Step by step:
Write what you know: 2n = 78.
A sperm cell is a gamete, so it has n chromosomes.
Solve: n = 78 \div 2 = 39.
Answer: 39 chromosomes.
Check: at fertilization a sperm (39) joins an egg (39): 39 + 39 = 78, the normal number for a dog body cell ✓
Tip: gametes always carry half of the body-cell number, so that fertilization restores the full number. Do not halve twice, and do not give the 2n value for a sperm or an egg.
Question 8 of 36
Hot spotInside a Pancreas Cell
Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.
A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.
Click on the structure in the diagram that contains the DNA with the instructions for building the digestive enzyme.
Click on the figure to mark your answer (or focus it and use the arrow keys).
Hint
Ribosomes build proteins, but they follow instructions stored somewhere else in the cell. Where does a eukaryotic cell keep its DNA?
Step-by-step solution
Where the answer comes from: the passage says the enzymes are proteins built by ribosomes on the rough ER. The ribosomes do the building, but the instructions come from genes in DNA, and in a eukaryotic cell nearly all of the DNA is stored in the nucleus, the large round structure at the left of the diagram.
Step by step:
Translate the question: "instructions for building" a protein = a gene, which is part of the DNA.
Recall where DNA is kept: inside the nucleus.
A copy of the gene (a messenger molecule) leaves the nucleus and goes to the ribosomes on the rough ER, which build the enzyme.
Avoid the traps: the rough ER and its ribosomes build the protein; the Golgi packages it; mitochondria supply energy.
Answer: click the nucleus.
Check: the diagram shows a darker spot (the nucleolus) inside the nucleus; it is part of the nucleus, so a click there also counts.
Tip: separate the "plan" from the "factory": the nucleus holds the plan (DNA); ribosomes are the workers that read a copy of it.
Question 9 of 36
Counting Dividing Cells in an Onion Root
Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.
Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
Prophase: chromosomes thicken and become visible.
Metaphase: chromosomes line up across the middle of the cell.
Anaphase: the two copies of each chromosome are pulled to opposite ends.
Telophase: two new nuclei form, and the cell begins to split in two.
The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.
Which conclusion is best supported by the student's data?
Hint
Use the passage's rule: the fraction of cells in a stage estimates the fraction of time spent in that stage. Turn each count into a fraction of 200.
Step-by-step solution
Where the answer comes from: the graph shows 180 of the 200 cells in interphase. The passage says "the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes."
Step by step:
Fraction in interphase: \dfrac{180}{200} = 0.90 = 90\%.
So the cells spend about 90% of the cell cycle in interphase, growing and copying DNA, and only about 10% actually dividing.
Check the other choices against the graph:
Metaphase (4 cells) is not the longest stage of mitosis; prophase (12 cells) is.
Anaphase and telophase have 2 cells each, which is half of metaphase's 4, not twice.
Nothing in the data tells us whether cells are alive or dead; counting stages says nothing about that.
Answer: The cells spend about 90% of the cell cycle in interphase.
Tip: on data questions, compute a quick fraction or percent and match it to a choice. Reject any choice that brings in an idea the data never measured.
Question 10 of 36
Fill inCounting Dividing Cells in an Onion Root
Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.
Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
Prophase: chromosomes thicken and become visible.
Metaphase: chromosomes line up across the middle of the cell.
Anaphase: the two copies of each chromosome are pulled to opposite ends.
Telophase: two new nuclei form, and the cell begins to split in two.
The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.
What percent of the 200 observed cells were in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase)?
%
Type your answer in the box. Fractions like 3/4 are fine.
Hint
Add the counts for the four mitosis stages, then divide by the total number of cells.
Step-by-step solution
Where the answer comes from: the bar graph shows prophase 12, metaphase 4, anaphase 2 and telophase 2, out of 200 cells total.
Step by step:
Add the dividing cells: 12 + 4 + 2 + 2 = 20.
Divide by the total: \dfrac{20}{200} = 0.10.
Convert to a percent: 0.10 \times 100 = 10\%.
Check: the interphase cells are 180 of 200, which is 90\%. Then 90\% + 10\% = 100\% ✓
Answer: 10%. This fraction of dividing cells is sometimes called the mitotic index. A high mitotic index means a tissue is growing quickly, as in a root tip.
Tip: "percent of the total" always means (part ÷ whole) × 100. Make sure the whole is all the cells counted (200), not just the dividing ones.
Question 11 of 36
Two Ways Cells Divide
Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.
In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.
Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.
Based on the passage and the diagram, how many chromosomes are in each cell produced at the end of meiosis II in a fruit fly?
Hint
The diagram shows the cells at the end of meiosis II as n. What is n when 2n = 8?
Step-by-step solution
Where the answer comes from: the passage says "a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8." The diagram shows that the four cells at the end of meiosis II each have n chromosomes, half the parent's number.
Step by step:
Write what you know: 2n = 8.
Solve for n: n = 8 \div 2 = 4.
The diagram labels every cell after meiosis I and after meiosis II as n. Meiosis II separates the copies of each chromosome, so it does not halve the number again.
Answer: 4 chromosomes.
Why not 2? It is tempting to halve once in meiosis I and again in meiosis II. But the DNA was copied before meiosis began, so the second division only splits the copies. The diagram confirms this: both rows after meiosis I are labeled n.
Tip: read the labels on a process diagram carefully. They often answer the question if you translate symbols (2n, n) into numbers.
Question 12 of 36
Select allTwo Ways Cells Divide
Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.
In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.
Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.
Select all the statements that describe meiosis but not mitosis.
Select all that apply.
Hint
For each statement, ask two questions: Is it true of meiosis? Is it also true of mitosis? Choose only "yes, no."
Step-by-step solution
Where the answer comes from: the diagram shows mitosis making "2 cells, identical to the parent cell," while meiosis makes "4 cells (gametes), each with half the parent's chromosomes, genetically different." The passage adds that in meiosis I homologous chromosomes "pair up and may trade pieces in a process called crossing over," and that mitosis "lets an organism grow and replace worn-out or damaged cells."
Step by step:
Produces four cells from one parent cell: meiosis yes (4 cells), mitosis no (2). Select.
Produces cells with half the parent's chromosome number: meiosis yes (n), mitosis no (2n). Select.
Includes crossing over between homologous chromosomes: only in meiosis I. Select.
Produces cells identical to the parent cell: that describes mitosis. Do not select.
Helps the organism grow and repair tissue: mitosis. Do not select.
Starts with a parent cell that has 2n chromosomes: true of both processes, so it does not describe meiosis only. Do not select.
Answer: the three statements about four cells, half the chromosome number, and crossing over.
Tip: in "but not" questions, a statement that is true of both things is a trap. It is true, but it does not answer the question.
Question 13 of 36
Mitochondria in Specialized Cells
Cells in the body are specialized: their structures match their jobs. Mitochondria release energy from sugar in a process called cellular respiration, which uses oxygen and produces ATP, the molecule cells use for energy.
Researchers examined tissue samples from mammals and estimated what percentage of each cell's volume is made up of mitochondria. The table shows approximate results.
Cell type
Main job
Mitochondria (approx. % of cell volume)
Heart muscle cell
Contracts nonstop, about 60 to 100 times a minute, for life
30
Liver cell
Carries out hundreds of chemical reactions
20
Skeletal (leg) muscle cell
Contracts when the body moves
5
Fat cell
Stores energy as fat
2
Mature red blood cell
Carries oxygen from the lungs to other cells
0
As red blood cells in mammals mature, they lose their nucleus and their mitochondria. A mature red blood cell gets the small amount of energy it needs from a process that breaks down sugar without using oxygen.
Which conclusion is best supported by the information in the table?
Hint
Compare each cell's job with its mitochondria percentage. Which jobs go with the highest numbers?
Step-by-step solution
Where the answer comes from: the table pairs each job with a mitochondria percentage. The heart muscle cell, which "contracts nonstop… for life," has the highest value (30%). The liver cell, which "carries out hundreds of chemical reactions," is next (20%). Cells with lighter energy demands (fat storage, 2%) have far less, and the red blood cell has none.
Step by step:
Rank the cells by mitochondria: heart 30 > liver 20 > skeletal muscle 5 > fat 2 > red blood cell 0.
Match to jobs: the top two do constant, energy-hungry work; the bottom cells store energy or simply carry oxygen.
Conclusion: cells that do continuous, energy-demanding work tend to devote more of their volume to mitochondria.
Check the others: the table gives no cell sizes; skeletal muscle (5) has less than heart muscle (30); and the passage never says fat cells lack sugar.
Answer: Cells that do continuous, energy-demanding work tend to have more of their volume made of mitochondria.
Tip: "best supported" means the conclusion must follow from the data shown. Watch for choices that sneak in data the table does not contain (like cell size).
Question 14 of 36
Drop-down
Select the words that correctly complete this summary of the cell theory.
All living things are made of one or more . The cell is the basic unit of . All cells come from .
Choose an answer from each menu.
Hint
The cell theory has three parts, and the third part disproved the old idea that life can arise from nonliving things.
Step-by-step solution
The cell theory is one of the foundational theories of biology. It was developed in the 1800s as microscopes improved:
Matthias Schleiden (1838) concluded that plants are made of cells, and Theodor Schwann (1839) concluded the same for animals.
Rudolf Virchow (1855) added that every cell comes from a cell that existed before it.
The three parts:
All living things are made of one or more cells. (Bacteria are one cell; a person is trillions.)
The cell is the basic unit of structure and function in living things: the smallest unit that can carry out all life processes.
All cells come from pre-existing cells, by cell division.
Why the wrong items fail: atoms make up everything, living or not, so they do not define life. Tissues exist only in multicellular organisms, so a one-celled bacterium has none. The idea that cells arise from mud or dust is spontaneous generation, which experiments in the 1800s disproved.
Answer: cells; structure and function in living things; pre-existing cells.
Tip: a scientific theory is a well-tested explanation supported by much evidence, not a guess. GED questions may ask which observation supports one part of a theory.
Question 15 of 36
Drag and dropFour Mystery Samples
A lab technician examined cells from four unlabeled samples with a powerful microscope. She knows that one sample is a bacterium, one is from an animal, one is from the leaf of a green plant, and one is from a mushroom (a fungus). Fungus cells have a nucleus and a cell wall but no chloroplasts. She recorded which structures she saw and the typical width of the cells.
Structure
Sample 1
Sample 2
Sample 3
Sample 4
Cell membrane
Yes
Yes
Yes
Yes
Ribosomes
Yes
Yes
Yes
Yes
Nucleus
No
Yes
Yes
Yes
Mitochondria
No
Yes
Yes
Yes
Cell wall
Yes
Yes
Yes
No
Chloroplasts
No
No
Yes
No
Typical width (micrometers)
2
8
40
20
Drag a sample into each box to identify the source of the cells. One sample is not used.
Bacterium
Animal
Green plant leaf
Tap a tile, then tap a box to place it.
Hint
Use one "clue" structure for each box: no nucleus → ?; no cell wall → ?; chloroplasts → ?
Step-by-step solution
Where the answer comes from: the table rows for Nucleus, Cell wall and Chloroplasts are the only ones that differ. The passage adds that "Fungus cells have a nucleus and a cell wall but no chloroplasts."
Step by step:
Bacterium: the only cell with no nucleus (and no mitochondria) is Sample 1.
Animal: animal cells have a nucleus but no cell wall. Only Sample 4 has "No" in the Cell wall row.
Green plant leaf: leaf cells carry out photosynthesis in chloroplasts. Only Sample 3 has chloroplasts (and it has a cell wall, as plant cells do).
Not used: Sample 2 has a nucleus and a cell wall but no chloroplasts, which matches the description of the fungus.
Check: every sample is used once at most, and each box matches exactly one clue.
Tip: rows where every sample says "Yes" (membrane, ribosomes) are useless for sorting. Cross them out first and focus on the rows that differ.
Question 16 of 36
How the Cell Theory Developed
The cell theory grew out of nearly 200 years of observations.
Year
Scientist
Observation or conclusion
1665
Robert Hooke
Looked at a thin slice of cork through an early microscope, saw tiny empty boxes, and called them cells.
1670s
Antonie van Leeuwenhoek
Using lenses he made himself, saw living single-celled organisms swimming in pond water.
1838
Matthias Schleiden
Concluded that all plants are made of cells.
1839
Theodor Schwann
Concluded that all animals are made of cells.
1855
Rudolf Virchow
Stated that every cell comes from a cell that existed before it.
1859–1862
Louis Pasteur
Boiled meat broth in flasks with long, bent necks. The broth stayed free of microbes as long as dust from the air could not reach it, but microbes grew once the neck was broken off.
Together, these findings support the three parts of the cell theory: all living things are made of one or more cells; the cell is the basic unit of structure and function in living things; and all cells come from pre-existing cells.
Scientists discover a tiny organism that has never been seen before, living near a hot-water vent on the deep ocean floor. According to the cell theory, which statement must be true of this organism?
Hint
The cell theory has three parts. Which choice follows from them for every living thing, whatever its size or home?
Step-by-step solution
Where the answer comes from: the passage ends with the three parts of the cell theory: "all living things are made of one or more cells; the cell is the basic unit of structure and function in living things; and all cells come from pre-existing cells."
Step by step:
Part 1 says every living thing is made of one or more cells. So the organism has at least one cell, but it could be single-celled.
Part 3 says every cell comes from a cell that existed before it. So its cells came from earlier cells.
The theory says nothing about a nucleus: bacteria are living cells without one.
Cells forming from minerals in vent water would be spontaneous generation, which Pasteur's experiment argued against.
Answer: It is made of at least one cell, and its cells came from earlier cells.
Check: this statement uses only parts of the theory, so it must be true for any organism, known or new.
Tip: "must be true" questions reward the choice that follows directly from the rule. Choices that add extra details (a nucleus, many cells) go beyond what the rule promises.
Question 17 of 36
Drop-down
Select the word that correctly completes each sentence.
A single heart muscle cell contains many , such as mitochondria. Millions of these cells working together form cardiac muscle . Cardiac muscle, nerve tissue and connective tissue together make up the heart, which is an .
Choose an answer from each menu.
Hint
Work from small to large: structures inside a cell → groups of similar cells → several kinds of tissue working together.
Step-by-step solution
Where the answer comes from: each sentence describes one step on the ladder organelle → cell → tissue → organ → organ system.
Step by step:
Mitochondria are structures inside a cell, so they are organelles.
Many similar cells doing one job (contracting) form a tissue: cardiac muscle tissue.
The heart is made of several kinds of tissue (muscle, nerve, connective) working together, which is the definition of an organ.
The heart is only one part of the circulatory system; the system also includes the blood vessels and blood. So the heart alone is not an organ system.
Answer: organelles; tissue; organ.
Check: read the sentences in order and the sizes grow at each step: organelle < cell < tissue < organ ✓
Tip: a single organ does not make a system. A system needs several organs, such as heart + blood vessels in the circulatory system.
Question 18 of 36
Hot spotInside a Pancreas Cell
Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.
A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.
Click on the structure in the diagram that modifies the enzyme and packages it into vesicles before it leaves the cell.
Click on the figure to mark your answer (or focus it and use the arrow keys).
Hint
Follow the path in paragraph 2: ribosomes and ER → ? → vesicles → cell membrane.
Step-by-step solution
Where the answer comes from: paragraph 2 says: "Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles." In the diagram, the Golgi apparatus is the stack of curved, flattened sacs to the right of the rough ER.
Step by step:
List the path: rough ER (build) → Golgi apparatus (modify and package) → vesicles (carry) → cell membrane (release).
The job in the question, "modifies" and "packages into vesicles," is the Golgi's step.
Find the Golgi label in the diagram and click the stack of sacs.
Traps: the vesicles are the packages themselves, not the packer; the rough ER builds and carries the protein before packaging.
Answer: click the Golgi apparatus.
Check: the vesicles in the diagram sit right next to the Golgi, on the side toward the cell membrane, which fits the path.
Tip: think of the Golgi as the cell's post office: it labels, wraps and ships proteins.
Question 19 of 36
Dividing Cells in Normal and Tumor Tissue
Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.
The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.
Stage
Normal skin (cells)
Skin tumor (cells)
Interphase
485
410
Prophase
8
50
Metaphase
3
20
Anaphase
2
10
Telophase
2
10
Total
500
500
Which conclusion about the normal and tumor tissue is best supported by the pathologist's counts?
Hint
Add up the cells in the four mitosis stages for each tissue. Then compare, and reject any choice about something the pathologist never measured.
Step-by-step solution
Where the answer comes from: the table shows, out of 500 cells each, the number in each stage. Dividing cells (prophase + metaphase + anaphase + telophase):
Normal skin: 8 + 3 + 2 + 2 = 15
Skin tumor: 50 + 20 + 10 + 10 = 90
Step by step:
Because both samples have 500 cells, the counts can be compared directly: 90 dividing tumor cells vs. 15 dividing normal cells.
So a much greater share of tumor cells were dividing, which fits the passage's statement that cancer cells divide "without the controls that normally stop them."
Check the other choices: 410 tumor cells were still in interphase, so they do not skip it; 15 normal cells were dividing, so normal skin cells do divide; and chromosome numbers were never counted.
Answer: A greater share of the tumor cells than of the normal skin cells were dividing.
Check: as percents, 15/500 = 3% and 90/500 = 18%; 18% is six times 3%.
Tip: the words never, skip and all are red flags. One counter-example in the table (15 dividing normal cells) is enough to reject them.
Question 20 of 36
Why Cells Stay Small
A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.
A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.
Side length (cm)
Surface area (cm²)
Volume (cm³)
Surface area-to-volume ratio
Volume turned pink (%)
1
6
1
6 : 1
100
2
24
8
3 : 1
88
3
54
27
2 : 1
70
Based on the table, which conclusion about cube size and the spread of the base is best supported?
Hint
Look at two columns together: what happens to the surface area-to-volume ratio as the cubes get bigger, and what happens to the percent that turned pink?
Step-by-step solution
Where the answer comes from: the table shows that as side length grows from 1 to 3 cm, the surface area-to-volume ratio falls from 6 : 1 to 3 : 1 to 2 : 1, and the volume turned pink falls from 100% to 88% to 70%. The passage says "the base had soaked in about 0.5 cm from each face" in every cube.
Step by step:
The base moved the same distance (0.5 cm) into every cube, so the speed of diffusion did not change.
In a bigger cube, more of the volume lies farther than 0.5 cm from any face, so a smaller fraction is reached.
The bigger the cube, the smaller its surface area compared with its volume, and the smaller the share that the base reached.
Answer: As cube size increased, the surface area-to-volume ratio decreased and a smaller percent of the volume was reached by the base.
Check: the largest cube (3 cm) has the biggest surface area (54 cm²) but the lowest percent pink (70%), so "more surface area" alone does not mean better supply; the ratio is what matters.
Tip: when a table has several columns, the best conclusion usually links the variable that was changed (size) to the result that was measured (percent pink).
Question 21 of 36
Potato Cores in Salt Water
A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.
Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.
Salt concentration (%)
Starting mass (g)
Mass after 24 hours (g)
Change in mass (%)
0 (distilled water)
5.00
5.60
+12
1
4.00
4.12
+3
2
5.00
4.80
−4
4
4.00
3.56
−11
6
5.00
4.20
−16
Based on the data, at about what salt concentration would a potato core neither gain nor lose mass?
Hint
Look at the "Change in mass" column. Where does the change switch from a gain (+) to a loss (−)?
Step-by-step solution
Where the answer comes from: the table shows a gain at 1% salt (+3%) and a loss at 2% salt (−4%).
Step by step:
A core keeps the same mass when water moves in and out equally, which happens when the solution has about the same concentration of dissolved particles as the potato cells.
The change in mass is positive up to 1% and negative from 2% on. Somewhere between 1% and 2% it must pass through zero.
The gain at 1% (+3) and the loss at 2% (−4) are similar in size, so the zero point is near the middle, roughly 1.4%. Any value between 1% and 2% fits.
Answer: between 1% and 2% salt.
Check: at 0% and 1% water moved into the cores (gain); at 2%, 4% and 6% water moved out (loss). Only the gap from 1% to 2% contains the switch.
Tip: to find where a change equals zero, look for the place where the sign changes from + to −. The answer lies between those two rows.
Question 22 of 36
Drag and dropChromosome Numbers in Different Species
Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.
Organism
Chromosomes in a body cell (2n)
Fruit fly
8
Corn
20
Cat
38
Human
46
Chimpanzee
48
Potato
48
Dog
78
Drag a statement into each box to show whether it is true of mitosis only, meiosis only, or both. One statement is not used.
Mitosis only
Meiosis only
Both mitosis and meiosis
Tap a tile, then tap a box to place it.
Hint
Recall which process makes body cells and which makes gametes. Then look for a step that happens before any cell divides.
Step-by-step solution
Where the answer comes from: the passage says gametes "are made by meiosis and have half that number (n)," while body cells divide by mitosis, "which keeps the chromosome number the same."
Step by step:
Mitosis only: "Produces two cells with the same chromosome number as the parent cell." A dog skin cell (78) makes two cells with 78 each.
Meiosis only: "Produces gametes with half the parent cell's chromosome number." A dog sperm has 39.
Both: "The cell copies its DNA before it starts dividing." Both processes begin with a copied set of chromosomes.
Not used: "Takes place only in plant cells" is false. Animals use both processes, and so do plants (corn and potato in the table).
Answer: Mitosis only = two cells with the same number; Meiosis only = gametes with half the number; Both = DNA is copied first.
Check: each statement fits exactly one box, and the leftover statement is false for both processes.
Tip: "same number, two cells" = mitosis (growth and repair); "half the number, four gametes" = meiosis (reproduction).
Question 23 of 36
Fill inDividing Cells in Normal and Tumor Tissue
Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.
The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.
Stage
Normal skin (cells)
Skin tumor (cells)
Interphase
485
410
Prophase
8
50
Metaphase
3
20
Anaphase
2
10
Telophase
2
10
Total
500
500
What is the mitotic index of the skin tumor sample?
%
Type your answer in the box. Fractions like 3/4 are fine.
Hint
Add the tumor cells in prophase, metaphase, anaphase and telophase. Divide by all the tumor cells counted, then turn the decimal into a percent.
Step-by-step solution
Where the answer comes from: the passage defines the mitotic index as "the percent of cells that are in one of the four stages of mitosis." The tumor column shows prophase 50, metaphase 20, anaphase 10 and telophase 10, out of 500 cells.
Divide by the whole sample: \dfrac{90}{500} = 0.18.
Convert to a percent: 0.18 \times 100 = 18\%.
Answer: 18%.
Check: the interphase tumor cells are 410 of 500, or 82\%, and 82\% + 18\% = 100\% ✓
Tip: the whole for a mitotic index is all the cells counted (500), not just the dividing cells and not the interphase cells. Using 410 as the whole would give about 22%, a common mistake.
Question 24 of 36
Drop-downWhy Cells Stay Small
A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.
A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.
Side length (cm)
Surface area (cm²)
Volume (cm³)
Surface area-to-volume ratio
Volume turned pink (%)
1
6
1
6 : 1
100
2
24
8
3 : 1
88
3
54
27
2 : 1
70
Select the words that correctly complete the description of the students' experiment.
The independent variable was . The dependent variable was . One variable the students kept the same for all cubes was .
Choose an answer from each menu.
Hint
The independent variable is what the students chose to change. The dependent variable is what they measured as a result.
Step-by-step solution
Where the answer comes from: the passage says the students "cut cubes that were 1 cm, 2 cm and 3 cm on each side" (what they changed), "placed all the cubes in the same dilute base solution for 10 minutes" (what they kept the same), and "estimated what percent of each cube's volume had turned pink" (what they measured).
Step by step:
Independent variable = the factor deliberately changed: the side length (size) of the cube.
Dependent variable = the result measured: the percent of the cube's volume that turned pink.
Controlled variables = everything kept the same so the test is fair: the time in the solution (10 minutes), the same base solution and the same agar recipe.
The depth the base soaked in (0.5 cm) was an observation, not something the students set.
Answer: the side length of the cube; the percent of the volume that turned pink; the time the cubes spent in the solution.
Check: say it as a sentence: "Changing the cube size affects the percent turned pink," with time kept the same ✓
Tip: a quick test is "I changed ___ and measured ___." The first blank is independent, the second is dependent, and everything else should be controlled.
Question 25 of 36
Counting Dividing Cells in an Onion Root
Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.
Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
Prophase: chromosomes thicken and become visible.
Metaphase: chromosomes line up across the middle of the cell.
Anaphase: the two copies of each chromosome are pulled to opposite ends.
Telophase: two new nuclei form, and the cell begins to split in two.
The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.
Suppose the complete cell cycle of these onion root-tip cells takes 24 hours. Based on the student's data, about how long does metaphase last?
Hint
First find the fraction of all 200 cells that were in metaphase. Then take that fraction of 24 hours, and convert hours to minutes.
Step-by-step solution
Where the answer comes from: the graph shows 4 cells in metaphase out of 200 total. The passage says the fraction of cells in a stage "estimates the fraction of the whole cell cycle that the stage takes."
Step by step:
Fraction in metaphase: \dfrac{4}{200} = 0.02.
Time in metaphase: 0.02 \times 24\text{ h} = 0.48\text{ h}.
48 minutes reads 0.48 hours as "48 minutes." An hour has 60 minutes, not 100.
4.8 hours uses only the 20 dividing cells as the whole: \tfrac{4}{20} \times 24 = 4.8. But the cycle includes interphase, so the whole is all 200 cells.
Tip: in multi-step problems, write the units at every step. Converting decimal hours to minutes (multiply by 60) is a classic GED trap.
Question 26 of 36
Two Ways Cells Divide
Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.
In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.
Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.
Human body cells have 46 chromosomes. Based on the passage, which statement best explains why human gametes must be made by meiosis rather than by mitosis?
Hint
Trace the chromosome number through one generation: gamete + gamete → zygote. What would happen if each gamete had 46?
Step-by-step solution
Where the answer comes from: the diagram shows that meiosis produces cells with n, half the parent's chromosomes, while mitosis keeps 2n. The passage says that "at fertilization, a sperm and an egg join to form a single cell called a zygote."
Step by step:
Human body cells: 2n = 46, so n = 23.
Meiosis gives each sperm and each egg 23 chromosomes.
Fertilization: 23 + 23 = 46. The zygote has the same number as each parent's body cells.
If gametes were made by mitosis, each would have 46, and the zygote would have 46 + 46 = 92. The number would double every generation.
Answer: Meiosis gives each gamete 23 chromosomes, so a sperm and an egg together restore the normal 46 in the zygote.
Why the others fail: choice B gets the numbers wrong (meiosis halves, it does not keep 46). Choice C is false: mitosis happens throughout the body, and the passage never says otherwise. Choice D contradicts the diagram, which says meiosis makes "genetically different" cells.
Tip: for chromosome questions, write the numbers at each step (body cell → gamete → zygote). The math reveals the answer.
Question 27 of 36
Potato Cores in Salt Water
A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.
Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.
Salt concentration (%)
Starting mass (g)
Mass after 24 hours (g)
Change in mass (%)
0 (distilled water)
5.00
5.60
+12
1
4.00
4.12
+3
2
5.00
4.80
−4
4
4.00
3.56
−11
6
5.00
4.20
−16
Why is the percent change in mass a better way than the change in grams to compare the cores in this experiment?
Hint
Look at the starting masses in the table. Are they all the same?
Step-by-step solution
Where the answer comes from: the table shows that the cores did not all start at the same mass: some started at 5.00 g and others at 4.00 g.
Step by step:
A heavier core has more cells, so it can gain or lose more grams of water even if each cell changes by the same amount.
The percent change divides the change by the starting mass, which removes the effect of size: \text{percent change} = \dfrac{\text{final} - \text{start}}{\text{start}} \times 100.
Example: the 1% core gained 4.12 - 4.00 = 0.12 g, which is \dfrac{0.12}{4.00} \times 100 = 3\%. A 5.00 g core changing by 3% would gain 0.15 g. In grams these look different, but in percent they are the same.
Answer: The cores started with different masses, and percent change allows a fair comparison between cores of different sizes.
Check: if all cores had started at exactly 5.00 g, grams and percent would rank the cores in the same order, so the starting masses are the reason percent is needed here.
Tip: use percent (or rate per unit) whenever the starting amounts differ. It turns unequal starting points into a fair comparison.
Question 28 of 36
How the Cell Theory Developed
The cell theory grew out of nearly 200 years of observations.
Year
Scientist
Observation or conclusion
1665
Robert Hooke
Looked at a thin slice of cork through an early microscope, saw tiny empty boxes, and called them cells.
1670s
Antonie van Leeuwenhoek
Using lenses he made himself, saw living single-celled organisms swimming in pond water.
1838
Matthias Schleiden
Concluded that all plants are made of cells.
1839
Theodor Schwann
Concluded that all animals are made of cells.
1855
Rudolf Virchow
Stated that every cell comes from a cell that existed before it.
1859–1862
Louis Pasteur
Boiled meat broth in flasks with long, bent necks. The broth stayed free of microbes as long as dust from the air could not reach it, but microbes grew once the neck was broken off.
Together, these findings support the three parts of the cell theory: all living things are made of one or more cells; the cell is the basic unit of structure and function in living things; and all cells come from pre-existing cells.
Which finding in the timeline provides experimental evidence for the idea that new cells come only from pre-existing cells?
Hint
An experiment tests an idea by changing one condition and watching the result. Which entry describes a test like that about where living cells come from?
Step-by-step solution
Where the answer comes from: the 1859–1862 entry says Pasteur's boiled broth "stayed free of microbes as long as dust from the air could not reach it, but microbes grew once the neck was broken off."
Step by step:
The idea being tested: can living cells (microbes) appear on their own from nonliving broth, or must they come from other cells?
Pasteur changed one condition: whether dust (which carries microbes) could reach the broth.
Result: no dust, no microbes; once dust could enter, microbes grew. So the microbes came from existing microbes, not from the broth itself.
Virchow also stated that cells come from cells, but the timeline describes his entry as a statement, not an experiment. Hooke, Leeuwenhoek and Schwann made observations that support other parts of the theory.
Answer: Pasteur's experiments with broth in bent-neck flasks.
Check: Pasteur's is the only entry with a condition that was changed and a result that was compared, which is what makes it an experiment.
Tip: match the evidence to the exact claim. "All animals are made of cells" is true, but it supports a different part of the theory.
Question 29 of 36
Fill inWhy Cells Stay Small
A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.
A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.
Side length (cm)
Surface area (cm²)
Volume (cm³)
Surface area-to-volume ratio
Volume turned pink (%)
1
6
1
6 : 1
100
2
24
8
3 : 1
88
3
54
27
2 : 1
70
Suppose the students also made a cube that is 4 cm on each side. What would its surface area-to-volume ratio be?
Enter your answer as the number that goes before ": 1".
: 1
Type your answer in the box. Fractions like 3/4 are fine.
Hint
Surface area of a cube = 6 × side × side. Volume = side × side × side. Then divide surface area by volume.
Step-by-step solution
Where the answer comes from: the passage defines surface area as "the total area of its six faces" and the table shows how the ratio was found for the other cubes (for example, 24 cm² ÷ 8 cm³ = 3 for the 2 cm cube).
Step by step:
Area of one face: 4 \times 4 = 16\text{ cm}^2.
Surface area (six faces): 6 \times 16 = 96\text{ cm}^2.
Volume: 4 \times 4 \times 4 = 64\text{ cm}^3.
Ratio: \dfrac{96}{64} = 1.5, so the ratio is 1.5 : 1.
Answer: 1.5 : 1.
Check: the pattern in the table is ratio = 6 ÷ side: 6 \div 1 = 6, 6 \div 2 = 3, 6 \div 3 = 2, so 6 \div 4 = 1.5 ✓ The ratio keeps falling as the cube grows.
Tip: surface area grows with the square of the side, but volume grows with the cube, so volume always wins as size increases. That is why the ratio shrinks.
Question 30 of 36
Fill inPotato Cores in Salt Water
A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.
Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.
Salt concentration (%)
Starting mass (g)
Mass after 24 hours (g)
Change in mass (%)
0 (distilled water)
5.00
5.60
+12
1
4.00
4.12
+3
2
5.00
4.80
−4
4
4.00
3.56
−11
6
5.00
4.20
−16
A different core from the same potato has a starting mass of 6.00 g. Based on the table, predict its mass after 24 hours in the 4% salt solution.
g
Type your answer in the box. Fractions like 3/4 are fine.
Hint
Use the percent change for 4% salt, not the change in grams, because this core is a different size.
Step-by-step solution
Where the answer comes from: the table shows a change in mass of −11% for the 4% salt solution (4.00 g → 3.56 g).
Step by step:
A core from the same potato should change by the same percent in the same solution, whatever its size.
The core loses this mass: 6.00 - 0.66 = 5.34\text{ g}.
(Or in one step: 6.00 \times 0.89 = 5.34.)
Answer: about 5.34 g.
Check:\dfrac{5.34 - 6.00}{6.00} \times 100 = -11\% ✓ The common mistake is to subtract the grams lost by the 4.00 g core (0.44 g), which gives 5.56 g; a bigger core loses more grams.
Tip: when sizes differ, carry the percent over to the new case, not the raw change. That is the reason the student calculated percents in the first place.
Question 31 of 36
Chromosome Numbers in Different Species
Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.
Organism
Chromosomes in a body cell (2n)
Fruit fly
8
Corn
20
Cat
38
Human
46
Chimpanzee
48
Potato
48
Dog
78
One cell in a dog's skin divides by mitosis. One cell in a dog's testis divides by meiosis to make sperm. Which statement correctly compares the cells produced by the two processes?
Hint
Find the dog's 2n in the table. How many cells does each process make, and does the chromosome number stay the same or get cut in half?
Step-by-step solution
Where the answer comes from: the table gives the dog 78 chromosomes (2n). The passage says meiosis makes gametes with "half that number (n)" and mitosis "keeps the chromosome number the same."
Step by step:
Mitosis: one skin cell → 2 cells, each with the same number: 78.
Meiosis: one cell → 4 cells (after meiosis I and II), each with half the number: 78 \div 2 = 39.
Mitosis copies are identical to the parent; meiosis products are genetically different from each other.
Answer: Mitosis produces 2 cells with 78 chromosomes each; meiosis produces 4 cells with 39 chromosomes each.
Check: a sperm (39) plus an egg (39) gives a zygote with 78, the normal dog number, and the zygote then grows by mitosis, keeping 78 in every body cell ✓
Tip: remember two numbers for each process: mitosis = 2 cells, 2n; meiosis = 4 cells, n.
Question 32 of 36
Inside a Pancreas Cell
Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.
A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.
A fat cell mainly stores fat and makes very few proteins for export. Compared with a fat cell, a pancreas cell like the one in the passage would be expected to have
Hint
Which organelles does paragraph 2 say are used to build, process and ship proteins? A cell that exports a lot of protein needs more of them.
Step-by-step solution
Where the answer comes from: paragraph 2 traces exported proteins through the cell: ribosomes on the "rough endoplasmic reticulum (ER) build the protein," then "the Golgi apparatus modifies the protein and packages it into small sacs called vesicles," and "Mitochondria supply the ATP for all of this work."
Step by step:
The pancreas cell's job is to make and export large amounts of enzyme protein.
The organelles in that pathway are the rough ER (with ribosomes) and the Golgi apparatus.
Structure matches function: a cell that exports much protein should have much more rough ER and Golgi than a cell that exports little.
Reject the others: protein export uses ATP, so fewer mitochondria makes no sense; animal cells such as these have no cell wall or chloroplasts.
Answer: much more rough ER and a larger Golgi apparatus.
Check: the diagram itself shows the rough ER and Golgi taking up a large part of the pancreas cell, which fits its job.
Tip: on structure-function questions, list the cell's main job, then name the organelle that does that job. More of the job → more of that organelle.
Question 33 of 36
Potato Cores in Salt Water
A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.
Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.
Salt concentration (%)
Starting mass (g)
Mass after 24 hours (g)
Change in mass (%)
0 (distilled water)
5.00
5.60
+12
1
4.00
4.12
+3
2
5.00
4.80
−4
4
4.00
3.56
−11
6
5.00
4.20
−16
Which change to the student's method would most improve the reliability of her results?
Hint
Reliable results can be repeated. How many cores did she test at each salt concentration?
Step-by-step solution
Where the answer comes from: the passage says the student "cut five cylinders (cores)" and placed each one in a different salt solution. So there was only one core for each concentration.
Step by step:
With one core per concentration, a single odd core (a damaged one, or one from a part of the potato with more sugar) could make that result wrong, and she would not know.
Testing several cores at each concentration and averaging their percent changes reduces the effect of any one unusual core.
The other choices do not repeat the test: changing the time or the salt in only some cups adds new variables, and skipping the blotting adds error from surface water.
Answer: Test several cores at each salt concentration and average the results.
Check: after the change, the independent variable (salt concentration) and the dependent variable (percent change in mass) stay the same; only the number of trials goes up.
Tip: on the GED, "more reliable" almost always means repeated trials or a larger sample, with everything else kept the same.
Question 34 of 36
Mitochondria in Specialized Cells
Cells in the body are specialized: their structures match their jobs. Mitochondria release energy from sugar in a process called cellular respiration, which uses oxygen and produces ATP, the molecule cells use for energy.
Researchers examined tissue samples from mammals and estimated what percentage of each cell's volume is made up of mitochondria. The table shows approximate results.
Cell type
Main job
Mitochondria (approx. % of cell volume)
Heart muscle cell
Contracts nonstop, about 60 to 100 times a minute, for life
30
Liver cell
Carries out hundreds of chemical reactions
20
Skeletal (leg) muscle cell
Contracts when the body moves
5
Fat cell
Stores energy as fat
2
Mature red blood cell
Carries oxygen from the lungs to other cells
0
As red blood cells in mammals mature, they lose their nucleus and their mitochondria. A mature red blood cell gets the small amount of energy it needs from a process that breaks down sugar without using oxygen.
Based on the passage, which is the best explanation for why it is an advantage for mature red blood cells to lack mitochondria?
Hint
Re-read what mitochondria use during cellular respiration, and what red blood cells carry. Then reason about what would happen if the two were combined.
Step-by-step solution
Where the answer comes from: three pieces of the stimulus must be combined.
Paragraph 1: cellular respiration in mitochondria "uses oxygen."
The table: a red blood cell's job is to carry "oxygen from the lungs to other cells."
Final paragraph: a mature red blood cell gets "the small amount of energy it needs from a process that breaks down sugar without using oxygen."
Step by step:
If a red blood cell had mitochondria, they would use some of the oxygen the cell is supposed to deliver.
Without mitochondria, the red blood cell makes its energy without oxygen, so the oxygen it carries reaches other cells.
This is a structure–function match: the missing organelle helps the cell do its job.
Answer: Without mitochondria, the cells do not use up the oxygen they are delivering to other cells.
Why the distractors fail:
B contradicts the table: red blood cells have 0% mitochondria, so they cannot out-produce heart cells, which have 30%.
C contradicts the passage, which says a red blood cell needs "the small amount of energy it needs."
D contradicts the table: liver and muscle cells, which do not store fat, have many mitochondria.
Tip: hard GED inference items often require joining two separate pieces of the stimulus. Underline the key verb in each piece ("uses oxygen," "carries oxygen") and look for the link.
Question 35 of 36
Dividing Cells in Normal and Tumor Tissue
Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.
The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.
Stage
Normal skin (cells)
Skin tumor (cells)
Interphase
485
410
Prophase
8
50
Metaphase
3
20
Anaphase
2
10
Telophase
2
10
Total
500
500
A drug stops dividing cells at metaphase: the cells cannot move on to anaphase. Cells that are already past metaphase finish dividing normally. If a piece of the skin tumor is treated with the drug for a few hours and the cells are counted again, which change in the counts is most likely?
Hint
Picture the cells moving through the stages like cars through a road with a roadblock at metaphase. Where do they pile up, and which stages after the roadblock empty out?
Step-by-step solution
Where the answer comes from: the table shows the starting tumor counts: metaphase 20, anaphase 10, telophase 10. The question says cells "cannot move on to anaphase" but cells "already past metaphase finish dividing normally."
Step by step:
Cells keep arriving at metaphase from prophase, but none can leave it. The metaphase count goes up.
Cells already in anaphase and telophase finish dividing, and no new cells replace them. Those counts go down.
The drug acts only on dividing cells, so the overall pattern is a pile-up at metaphase and an empty space after it.
Answer: More cells would be in metaphase, and fewer cells would be in anaphase and telophase.
Check: this is how such drugs are used in real labs: blocking metaphase makes chromosomes easy to count, because many cells are held at that stage.
Tip: for "what would happen if" questions about a process with steps, find the blocked step: things build up before or at the block and run out after it.
Question 36 of 36
Why Cells Stay Small
A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.
A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.
Side length (cm)
Surface area (cm²)
Volume (cm³)
Surface area-to-volume ratio
Volume turned pink (%)
1
6
1
6 : 1
100
2
24
8
3 : 1
88
3
54
27
2 : 1
70
An elephant's body is made of trillions of small cells rather than a smaller number of very large cells. Based on the passage, which statement best explains why?
Hint
Use the agar results as a model of a cell. What happens to the share of a cell that materials can reach as the cell gets bigger?
Step-by-step solution
Where the answer comes from: the passage says that in a cell "materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them." The table shows that bigger cubes have a smaller surface area-to-volume ratio and that a smaller share of their volume is reached (100% → 88% → 70%).
Step by step:
Treat each cube as a model cell and the base as oxygen or nutrients.
In a large cell, the surface is small compared with the volume, so materials cannot reach the center quickly enough.
Many small cells each keep a high surface area-to-volume ratio, so every part of every cell gets supplied.
An elephant grows large by adding more cells, not by making each cell enormous.
Answer: Small cells have a large surface area compared with their volume, so materials can reach all parts of each cell quickly.
Check: an elephant's cells are about the same size as a mouse's cells; the elephant simply has many more of them, which fits this explanation.
Tip: when a passage uses a model (agar cubes), apply the model's result to the real thing it stands for (cells).