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Organization of life: cells, tissues, organisms

Question 1 of 36 · 0 right

Question 1 of 36

Two Cells Under the Microscope

A student looked at two kinds of cells under a light microscope. One sample was scraped gently from the inside of her cheek. The other was a thin leaf from a pond plant. She drew one cell from each sample, labeled the structures she could see, and named the drawings Cell X and Cell Y. Later she realized she had forgotten to write down which drawing came from which sample.

Her teacher reminded her that all plant and animal cells share some structures, such as a cell membrane, cytoplasm, a nucleus and mitochondria. Other structures are found only in certain kinds of cells, so they can be used as clues.

Diagram of two cells. Cell X (left) is round and flexible in outline. It has a cell membrane, cytoplasm, a nucleus with a nucleolus, and two mitochondria. It has no cell wall, no chloroplasts and no large vacuole. Cell Y (right) is box-shaped. It has a thick cell wall outside its cell membrane, a nucleus pushed to the upper left, one large central vacuole, two green chloroplasts (one at lower left below the nucleus, one at the bottom center) and one mitochondrion at the lower right. Cell X Nucleus Mitochondrion Cytoplasm Cell membrane Cell Y Vacuole Nucleus Chloroplast Mitochondrion Cell wall Cell membrane

Which statement correctly identifies Cell Y and gives evidence from the diagram that supports it?

Answer choices
Hint

Look for structures that appear in only one of the two drawings. Structures found in both cells cannot tell them apart.

Question 2 of 36

Hot spot
Two Cells Under the Microscope

A student looked at two kinds of cells under a light microscope. One sample was scraped gently from the inside of her cheek. The other was a thin leaf from a pond plant. She drew one cell from each sample, labeled the structures she could see, and named the drawings Cell X and Cell Y. Later she realized she had forgotten to write down which drawing came from which sample.

Her teacher reminded her that all plant and animal cells share some structures, such as a cell membrane, cytoplasm, a nucleus and mitochondria. Other structures are found only in certain kinds of cells, so they can be used as clues.

Diagram of two cells. Cell X (left) is round and flexible in outline. It has a cell membrane, cytoplasm, a nucleus with a nucleolus, and two mitochondria. It has no cell wall, no chloroplasts and no large vacuole. Cell Y (right) is box-shaped. It has a thick cell wall outside its cell membrane, a nucleus pushed to the upper left, one large central vacuole, two green chloroplasts (one at lower left below the nucleus, one at the bottom center) and one mitochondrion at the lower right. Cell X Nucleus Mitochondrion Cytoplasm Cell membrane Cell Y Vacuole Nucleus Chloroplast Mitochondrion Cell wall Cell membrane

Click on a structure in Cell Y where the energy of sunlight is captured and used to make sugar.

Click on the figure to mark your answer (or focus it and use the arrow keys).

Diagram of two cells. Cell X (left) is round and flexible in outline. It has a cell membrane, cytoplasm, a nucleus with a nucleolus, and two mitochondria. It has no cell wall, no chloroplasts and no large vacuole. Cell Y (right) is box-shaped. It has a thick cell wall outside its cell membrane, a nucleus pushed to the upper left, one large central vacuole, two green chloroplasts (one at lower left below the nucleus, one at the bottom center) and one mitochondrion at the lower right. Cell X Nucleus Mitochondrion Cytoplasm Cell membrane Cell Y Vacuole Nucleus Chloroplast Mitochondrion Cell wall Cell membrane
Hint

The process that uses light energy to make sugar is photosynthesis. Which organelle carries it out, and which cell in the diagram has it?

Question 3 of 36

Drag and drop

Drag the terms into the boxes to show the levels of organization in the human body, from smallest to largest. Two terms are not used.

SmallestLargest
CellOrganism

Tap a tile, then tap a box to place it.

Hint

Each level is made of many units of the level before it. What do you call a group of similar cells working together?

Question 4 of 36

Four Mystery Samples

A lab technician examined cells from four unlabeled samples with a powerful microscope. She knows that one sample is a bacterium, one is from an animal, one is from the leaf of a green plant, and one is from a mushroom (a fungus). Fungus cells have a nucleus and a cell wall but no chloroplasts. She recorded which structures she saw and the typical width of the cells.

StructureSample 1Sample 2Sample 3Sample 4
Cell membraneYesYesYesYes
RibosomesYesYesYesYes
NucleusNoYesYesYes
MitochondriaNoYesYesYes
Cell wallYesYesYesNo
ChloroplastsNoNoYesNo
Typical width (micrometers)284020

Which sample is most likely the bacterium, and what evidence in the table supports this?

Answer choices
Hint

Bacteria are prokaryotes. Which structure do prokaryotic cells lack that all the other cells have?

Question 5 of 36

The inner lining of the stomach is a thin layer made of many similar cells that work together to release digestive juices. At which level of organization is this layer best classified?

Answer choices
Hint

A group of similar cells doing one job together has a special name. It is one step above a single cell.

Question 6 of 36

Potato Cores in Salt Water

A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.

Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.

Salt concentration (%)Starting mass (g)Mass after 24 hours (g)Change in mass (%)
0 (distilled water)5.005.60+12
14.004.12+3
25.004.80−4
44.003.56−11
65.004.20−16

Which statement best explains why the potato core in distilled water gained mass?

Answer choices
Hint

Distilled water has no dissolved salt. Which side of the cell membrane has more dissolved particles: the water or the inside of the potato cells?

Question 7 of 36

Fill in
Chromosome Numbers in Different Species

Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.

OrganismChromosomes in a body cell (2n)
Fruit fly8
Corn20
Cat38
Human46
Chimpanzee48
Potato48
Dog78

Based on the table, how many chromosomes are in a sperm cell of a dog?

chromosomes

Type your answer in the box. Fractions like 3/4 are fine.

Hint

A sperm cell is a gamete. The passage tells you how a gamete's chromosome number compares with 2n.

Question 8 of 36

Hot spot
Inside a Pancreas Cell

Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.

A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.

Diagram of a pancreas cell that makes digestive enzymes. A large oval cell membrane surrounds everything. At the left is a round nucleus with a darker nucleolus. To its right are curved bands of rough endoplasmic reticulum (rough ER) dotted with ribosomes. Further right is the Golgi apparatus, a stack of curved flattened sacs, and beside it several small round vesicles near the right edge of the cell. Three bean-shaped mitochondria with folded inner membranes are scattered in the cytoplasm. Labels: Nucleus, Rough ER (with ribosomes), Golgi apparatus, Vesicles, Mitochondrion, Cell membrane. Nucleus Rough ER (with ribosomes) Golgi apparatus Vesicles Mitochondrion Cell membrane

Click on the structure in the diagram that contains the DNA with the instructions for building the digestive enzyme.

Click on the figure to mark your answer (or focus it and use the arrow keys).

Diagram of a pancreas cell that makes digestive enzymes. A large oval cell membrane surrounds everything. At the left is a round nucleus with a darker nucleolus. To its right are curved bands of rough endoplasmic reticulum (rough ER) dotted with ribosomes. Further right is the Golgi apparatus, a stack of curved flattened sacs, and beside it several small round vesicles near the right edge of the cell. Three bean-shaped mitochondria with folded inner membranes are scattered in the cytoplasm. Labels: Nucleus, Rough ER (with ribosomes), Golgi apparatus, Vesicles, Mitochondrion, Cell membrane. Nucleus Rough ER (with ribosomes) Golgi apparatus Vesicles Mitochondrion Cell membrane
Hint

Ribosomes build proteins, but they follow instructions stored somewhere else in the cell. Where does a eukaryotic cell keep its DNA?

Question 9 of 36

Counting Dividing Cells in an Onion Root

Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.

  • Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
  • Prophase: chromosomes thicken and become visible.
  • Metaphase: chromosomes line up across the middle of the cell.
  • Anaphase: the two copies of each chromosome are pulled to opposite ends.
  • Telophase: two new nuclei form, and the cell begins to split in two.

The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.

Bar graph: number of onion root-tip cells observed in each stage (200 cells in all). Interphase 180, prophase 12, metaphase 4, anaphase 2, telophase 2. 0 50 100 150 200 180 Interphase 12 Prophase 4 Metaphase 2 Anaphase 2 Telophase Stage of the cell cycle Number of cells

Which conclusion is best supported by the student's data?

Answer choices
Hint

Use the passage's rule: the fraction of cells in a stage estimates the fraction of time spent in that stage. Turn each count into a fraction of 200.

Question 10 of 36

Fill in
Counting Dividing Cells in an Onion Root

Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.

  • Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
  • Prophase: chromosomes thicken and become visible.
  • Metaphase: chromosomes line up across the middle of the cell.
  • Anaphase: the two copies of each chromosome are pulled to opposite ends.
  • Telophase: two new nuclei form, and the cell begins to split in two.

The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.

Bar graph: number of onion root-tip cells observed in each stage (200 cells in all). Interphase 180, prophase 12, metaphase 4, anaphase 2, telophase 2. 0 50 100 150 200 180 Interphase 12 Prophase 4 Metaphase 2 Anaphase 2 Telophase Stage of the cell cycle Number of cells

What percent of the 200 observed cells were in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase)?

%

Type your answer in the box. Fractions like 3/4 are fine.

Hint

Add the counts for the four mitosis stages, then divide by the total number of cells.

Question 11 of 36

Two Ways Cells Divide

Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.

In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.

Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.

Diagram comparing mitosis and meiosis. Mitosis: one parent cell with 2n chromosomes divides once into 2 identical cells, each 2n. Meiosis: one parent cell with 2n chromosomes divides in meiosis I into 2 cells, each n; in meiosis II each of those divides again, giving 4 cells (gametes), each n, meaning half the parent's chromosome number, and genetically different from one another. Mitosis 2n 2n 2n 2 cells, identical to the parent cell Meiosis 2n Meiosis I n n Meiosis II n n n n 4 cells (gametes), each with half the parent's chromosomes, genetically different

Based on the passage and the diagram, how many chromosomes are in each cell produced at the end of meiosis II in a fruit fly?

Answer choices
Hint

The diagram shows the cells at the end of meiosis II as n. What is n when 2n = 8?

Question 12 of 36

Select all
Two Ways Cells Divide

Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.

In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.

Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.

Diagram comparing mitosis and meiosis. Mitosis: one parent cell with 2n chromosomes divides once into 2 identical cells, each 2n. Meiosis: one parent cell with 2n chromosomes divides in meiosis I into 2 cells, each n; in meiosis II each of those divides again, giving 4 cells (gametes), each n, meaning half the parent's chromosome number, and genetically different from one another. Mitosis 2n 2n 2n 2 cells, identical to the parent cell Meiosis 2n Meiosis I n n Meiosis II n n n n 4 cells (gametes), each with half the parent's chromosomes, genetically different

Select all the statements that describe meiosis but not mitosis.

Select all that apply.

Answer choices
Hint

For each statement, ask two questions: Is it true of meiosis? Is it also true of mitosis? Choose only "yes, no."

Question 13 of 36

Mitochondria in Specialized Cells

Cells in the body are specialized: their structures match their jobs. Mitochondria release energy from sugar in a process called cellular respiration, which uses oxygen and produces ATP, the molecule cells use for energy.

Researchers examined tissue samples from mammals and estimated what percentage of each cell's volume is made up of mitochondria. The table shows approximate results.

Cell typeMain jobMitochondria (approx. % of cell volume)
Heart muscle cellContracts nonstop, about 60 to 100 times a minute, for life30
Liver cellCarries out hundreds of chemical reactions20
Skeletal (leg) muscle cellContracts when the body moves5
Fat cellStores energy as fat2
Mature red blood cellCarries oxygen from the lungs to other cells0

As red blood cells in mammals mature, they lose their nucleus and their mitochondria. A mature red blood cell gets the small amount of energy it needs from a process that breaks down sugar without using oxygen.

Which conclusion is best supported by the information in the table?

Answer choices
Hint

Compare each cell's job with its mitochondria percentage. Which jobs go with the highest numbers?

Question 14 of 36

Drop-down

Select the words that correctly complete this summary of the cell theory.

All living things are made of one or more . The cell is the basic unit of . All cells come from .

Choose an answer from each menu.

Hint

The cell theory has three parts, and the third part disproved the old idea that life can arise from nonliving things.

Question 15 of 36

Drag and drop
Four Mystery Samples

A lab technician examined cells from four unlabeled samples with a powerful microscope. She knows that one sample is a bacterium, one is from an animal, one is from the leaf of a green plant, and one is from a mushroom (a fungus). Fungus cells have a nucleus and a cell wall but no chloroplasts. She recorded which structures she saw and the typical width of the cells.

StructureSample 1Sample 2Sample 3Sample 4
Cell membraneYesYesYesYes
RibosomesYesYesYesYes
NucleusNoYesYesYes
MitochondriaNoYesYesYes
Cell wallYesYesYesNo
ChloroplastsNoNoYesNo
Typical width (micrometers)284020

Drag a sample into each box to identify the source of the cells. One sample is not used.

BacteriumAnimalGreen plant leaf

Tap a tile, then tap a box to place it.

Hint

Use one "clue" structure for each box: no nucleus → ?; no cell wall → ?; chloroplasts → ?

Question 16 of 36

How the Cell Theory Developed

The cell theory grew out of nearly 200 years of observations.

YearScientistObservation or conclusion
1665Robert HookeLooked at a thin slice of cork through an early microscope, saw tiny empty boxes, and called them cells.
1670sAntonie van LeeuwenhoekUsing lenses he made himself, saw living single-celled organisms swimming in pond water.
1838Matthias SchleidenConcluded that all plants are made of cells.
1839Theodor SchwannConcluded that all animals are made of cells.
1855Rudolf VirchowStated that every cell comes from a cell that existed before it.
1859–1862Louis PasteurBoiled meat broth in flasks with long, bent necks. The broth stayed free of microbes as long as dust from the air could not reach it, but microbes grew once the neck was broken off.

Together, these findings support the three parts of the cell theory: all living things are made of one or more cells; the cell is the basic unit of structure and function in living things; and all cells come from pre-existing cells.

Scientists discover a tiny organism that has never been seen before, living near a hot-water vent on the deep ocean floor. According to the cell theory, which statement must be true of this organism?

Answer choices
Hint

The cell theory has three parts. Which choice follows from them for every living thing, whatever its size or home?

Question 17 of 36

Drop-down

Select the word that correctly completes each sentence.

A single heart muscle cell contains many , such as mitochondria. Millions of these cells working together form cardiac muscle . Cardiac muscle, nerve tissue and connective tissue together make up the heart, which is an .

Choose an answer from each menu.

Hint

Work from small to large: structures inside a cell → groups of similar cells → several kinds of tissue working together.

Question 18 of 36

Hot spot
Inside a Pancreas Cell

Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.

A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.

Diagram of a pancreas cell that makes digestive enzymes. A large oval cell membrane surrounds everything. At the left is a round nucleus with a darker nucleolus. To its right are curved bands of rough endoplasmic reticulum (rough ER) dotted with ribosomes. Further right is the Golgi apparatus, a stack of curved flattened sacs, and beside it several small round vesicles near the right edge of the cell. Three bean-shaped mitochondria with folded inner membranes are scattered in the cytoplasm. Labels: Nucleus, Rough ER (with ribosomes), Golgi apparatus, Vesicles, Mitochondrion, Cell membrane. Nucleus Rough ER (with ribosomes) Golgi apparatus Vesicles Mitochondrion Cell membrane

Click on the structure in the diagram that modifies the enzyme and packages it into vesicles before it leaves the cell.

Click on the figure to mark your answer (or focus it and use the arrow keys).

Diagram of a pancreas cell that makes digestive enzymes. A large oval cell membrane surrounds everything. At the left is a round nucleus with a darker nucleolus. To its right are curved bands of rough endoplasmic reticulum (rough ER) dotted with ribosomes. Further right is the Golgi apparatus, a stack of curved flattened sacs, and beside it several small round vesicles near the right edge of the cell. Three bean-shaped mitochondria with folded inner membranes are scattered in the cytoplasm. Labels: Nucleus, Rough ER (with ribosomes), Golgi apparatus, Vesicles, Mitochondrion, Cell membrane. Nucleus Rough ER (with ribosomes) Golgi apparatus Vesicles Mitochondrion Cell membrane
Hint

Follow the path in paragraph 2: ribosomes and ER → ? → vesicles → cell membrane.

Question 19 of 36

Dividing Cells in Normal and Tumor Tissue

Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.

The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.

StageNormal skin (cells)Skin tumor (cells)
Interphase485410
Prophase850
Metaphase320
Anaphase210
Telophase210
Total500500

Which conclusion about the normal and tumor tissue is best supported by the pathologist's counts?

Answer choices
Hint

Add up the cells in the four mitosis stages for each tissue. Then compare, and reject any choice about something the pathologist never measured.

Question 20 of 36

Why Cells Stay Small

A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.

A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.

Side length (cm)Surface area (cm²)Volume (cm³)Surface area-to-volume ratioVolume turned pink (%)
1616 : 1100
22483 : 188
354272 : 170

Based on the table, which conclusion about cube size and the spread of the base is best supported?

Answer choices
Hint

Look at two columns together: what happens to the surface area-to-volume ratio as the cubes get bigger, and what happens to the percent that turned pink?

Question 21 of 36

Potato Cores in Salt Water

A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.

Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.

Salt concentration (%)Starting mass (g)Mass after 24 hours (g)Change in mass (%)
0 (distilled water)5.005.60+12
14.004.12+3
25.004.80−4
44.003.56−11
65.004.20−16

Based on the data, at about what salt concentration would a potato core neither gain nor lose mass?

Answer choices
Hint

Look at the "Change in mass" column. Where does the change switch from a gain (+) to a loss (−)?

Question 22 of 36

Drag and drop
Chromosome Numbers in Different Species

Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.

OrganismChromosomes in a body cell (2n)
Fruit fly8
Corn20
Cat38
Human46
Chimpanzee48
Potato48
Dog78

Drag a statement into each box to show whether it is true of mitosis only, meiosis only, or both. One statement is not used.

Mitosis onlyMeiosis onlyBoth mitosis and meiosis

Tap a tile, then tap a box to place it.

Hint

Recall which process makes body cells and which makes gametes. Then look for a step that happens before any cell divides.

Question 23 of 36

Fill in
Dividing Cells in Normal and Tumor Tissue

Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.

The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.

StageNormal skin (cells)Skin tumor (cells)
Interphase485410
Prophase850
Metaphase320
Anaphase210
Telophase210
Total500500

What is the mitotic index of the skin tumor sample?

%

Type your answer in the box. Fractions like 3/4 are fine.

Hint

Add the tumor cells in prophase, metaphase, anaphase and telophase. Divide by all the tumor cells counted, then turn the decimal into a percent.

Question 24 of 36

Drop-down
Why Cells Stay Small

A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.

A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.

Side length (cm)Surface area (cm²)Volume (cm³)Surface area-to-volume ratioVolume turned pink (%)
1616 : 1100
22483 : 188
354272 : 170

Select the words that correctly complete the description of the students' experiment.

The independent variable was . The dependent variable was . One variable the students kept the same for all cubes was .

Choose an answer from each menu.

Hint

The independent variable is what the students chose to change. The dependent variable is what they measured as a result.

Question 25 of 36

Counting Dividing Cells in an Onion Root

Cells near the tip of a growing onion root divide often. A student stained a thin slice of root tip so that the chromosomes were easy to see. Under the microscope, she counted 200 cells and recorded the stage each cell was in.

  • Interphase: the cell grows and copies its DNA; chromosomes are not visible as separate strands.
  • Prophase: chromosomes thicken and become visible.
  • Metaphase: chromosomes line up across the middle of the cell.
  • Anaphase: the two copies of each chromosome are pulled to opposite ends.
  • Telophase: two new nuclei form, and the cell begins to split in two.

The cells in the root tip divide independently of one another, so at any moment they are spread across all stages. For that reason, the fraction of cells found in a stage estimates the fraction of the whole cell cycle that the stage takes.

Bar graph: number of onion root-tip cells observed in each stage (200 cells in all). Interphase 180, prophase 12, metaphase 4, anaphase 2, telophase 2. 0 50 100 150 200 180 Interphase 12 Prophase 4 Metaphase 2 Anaphase 2 Telophase Stage of the cell cycle Number of cells

Suppose the complete cell cycle of these onion root-tip cells takes 24 hours. Based on the student's data, about how long does metaphase last?

Answer choices
Hint

First find the fraction of all 200 cells that were in metaphase. Then take that fraction of 24 hours, and convert hours to minutes.

Question 26 of 36

Two Ways Cells Divide

Most body cells divide by mitosis. Mitosis lets an organism grow and replace worn-out or damaged cells. Sex cells, called gametes (sperm and eggs), are made by a different process called meiosis.

In the diagram, 2n stands for the full number of chromosomes in a body cell (the diploid number), and n stands for half that number (the haploid number). For example, a fruit fly body cell has 8 chromosomes, so for a fruit fly 2n = 8.

Before either kind of division, the cell copies its DNA. In meiosis I, matching chromosomes (one from each parent, called homologous chromosomes) pair up and may trade pieces in a process called crossing over. Then the pairs separate into two cells. In meiosis II, the two copies of each chromosome separate, so four cells form. At fertilization, a sperm and an egg join to form a single cell called a zygote, which grows into a new organism by mitosis.

Diagram comparing mitosis and meiosis. Mitosis: one parent cell with 2n chromosomes divides once into 2 identical cells, each 2n. Meiosis: one parent cell with 2n chromosomes divides in meiosis I into 2 cells, each n; in meiosis II each of those divides again, giving 4 cells (gametes), each n, meaning half the parent's chromosome number, and genetically different from one another. Mitosis 2n 2n 2n 2 cells, identical to the parent cell Meiosis 2n Meiosis I n n Meiosis II n n n n 4 cells (gametes), each with half the parent's chromosomes, genetically different

Human body cells have 46 chromosomes. Based on the passage, which statement best explains why human gametes must be made by meiosis rather than by mitosis?

Answer choices
Hint

Trace the chromosome number through one generation: gamete + gamete → zygote. What would happen if each gamete had 46?

Question 27 of 36

Potato Cores in Salt Water

A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.

Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.

Salt concentration (%)Starting mass (g)Mass after 24 hours (g)Change in mass (%)
0 (distilled water)5.005.60+12
14.004.12+3
25.004.80−4
44.003.56−11
65.004.20−16

Why is the percent change in mass a better way than the change in grams to compare the cores in this experiment?

Answer choices
Hint

Look at the starting masses in the table. Are they all the same?

Question 28 of 36

How the Cell Theory Developed

The cell theory grew out of nearly 200 years of observations.

YearScientistObservation or conclusion
1665Robert HookeLooked at a thin slice of cork through an early microscope, saw tiny empty boxes, and called them cells.
1670sAntonie van LeeuwenhoekUsing lenses he made himself, saw living single-celled organisms swimming in pond water.
1838Matthias SchleidenConcluded that all plants are made of cells.
1839Theodor SchwannConcluded that all animals are made of cells.
1855Rudolf VirchowStated that every cell comes from a cell that existed before it.
1859–1862Louis PasteurBoiled meat broth in flasks with long, bent necks. The broth stayed free of microbes as long as dust from the air could not reach it, but microbes grew once the neck was broken off.

Together, these findings support the three parts of the cell theory: all living things are made of one or more cells; the cell is the basic unit of structure and function in living things; and all cells come from pre-existing cells.

Which finding in the timeline provides experimental evidence for the idea that new cells come only from pre-existing cells?

Answer choices
Hint

An experiment tests an idea by changing one condition and watching the result. Which entry describes a test like that about where living cells come from?

Question 29 of 36

Fill in
Why Cells Stay Small

A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.

A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.

Side length (cm)Surface area (cm²)Volume (cm³)Surface area-to-volume ratioVolume turned pink (%)
1616 : 1100
22483 : 188
354272 : 170

Suppose the students also made a cube that is 4 cm on each side. What would its surface area-to-volume ratio be?

Enter your answer as the number that goes before ": 1".

: 1

Type your answer in the box. Fractions like 3/4 are fine.

Hint

Surface area of a cube = 6 × side × side. Volume = side × side × side. Then divide surface area by volume.

Question 30 of 36

Fill in
Potato Cores in Salt Water

A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.

Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.

Salt concentration (%)Starting mass (g)Mass after 24 hours (g)Change in mass (%)
0 (distilled water)5.005.60+12
14.004.12+3
25.004.80−4
44.003.56−11
65.004.20−16

A different core from the same potato has a starting mass of 6.00 g. Based on the table, predict its mass after 24 hours in the 4% salt solution.

g

Type your answer in the box. Fractions like 3/4 are fine.

Hint

Use the percent change for 4% salt, not the change in grams, because this core is a different size.

Question 31 of 36

Chromosome Numbers in Different Species

Every species has a typical number of chromosomes in its body cells, called the diploid number (2n). Gametes (sperm and egg cells) are made by meiosis and have half that number (n). Body cells divide by mitosis, which keeps the chromosome number the same.

OrganismChromosomes in a body cell (2n)
Fruit fly8
Corn20
Cat38
Human46
Chimpanzee48
Potato48
Dog78

One cell in a dog's skin divides by mitosis. One cell in a dog's testis divides by meiosis to make sperm. Which statement correctly compares the cells produced by the two processes?

Answer choices
Hint

Find the dog's 2n in the table. How many cells does each process make, and does the chromosome number stay the same or get cut in half?

Question 32 of 36

Inside a Pancreas Cell

Cells in the pancreas make digestive enzymes. Enzymes are proteins, and these cells release them into a tube that carries them to the small intestine. The diagram shows one of these cells.

A protein made for export follows a path through the cell. Ribosomes attached to the rough endoplasmic reticulum (ER) build the protein, and it travels through the channels of the ER. Next, the Golgi apparatus modifies the protein and packages it into small sacs called vesicles. The vesicles move to the cell membrane, join with it and release the protein outside the cell. Mitochondria supply the ATP for all of this work.

Diagram of a pancreas cell that makes digestive enzymes. A large oval cell membrane surrounds everything. At the left is a round nucleus with a darker nucleolus. To its right are curved bands of rough endoplasmic reticulum (rough ER) dotted with ribosomes. Further right is the Golgi apparatus, a stack of curved flattened sacs, and beside it several small round vesicles near the right edge of the cell. Three bean-shaped mitochondria with folded inner membranes are scattered in the cytoplasm. Labels: Nucleus, Rough ER (with ribosomes), Golgi apparatus, Vesicles, Mitochondrion, Cell membrane. Nucleus Rough ER (with ribosomes) Golgi apparatus Vesicles Mitochondrion Cell membrane

A fat cell mainly stores fat and makes very few proteins for export. Compared with a fat cell, a pancreas cell like the one in the passage would be expected to have

Answer choices
Hint

Which organelles does paragraph 2 say are used to build, process and ship proteins? A cell that exports a lot of protein needs more of them.

Question 33 of 36

Potato Cores in Salt Water

A student cut five cylinders (cores) from the same potato. She weighed each core, placed it in a cup holding 100 mL of a salt solution, and left all five cups at room temperature. After 24 hours she blotted each core dry with a paper towel and weighed it again. She then calculated the percent change in mass for each core.

Water crosses a cell membrane by osmosis: water moves from the side with fewer dissolved particles (more water) to the side with more dissolved particles (less water). Salt does not easily cross the membrane of a potato cell.

Salt concentration (%)Starting mass (g)Mass after 24 hours (g)Change in mass (%)
0 (distilled water)5.005.60+12
14.004.12+3
25.004.80−4
44.003.56−11
65.004.20−16

Which change to the student's method would most improve the reliability of her results?

Answer choices
Hint

Reliable results can be repeated. How many cores did she test at each salt concentration?

Question 34 of 36

Mitochondria in Specialized Cells

Cells in the body are specialized: their structures match their jobs. Mitochondria release energy from sugar in a process called cellular respiration, which uses oxygen and produces ATP, the molecule cells use for energy.

Researchers examined tissue samples from mammals and estimated what percentage of each cell's volume is made up of mitochondria. The table shows approximate results.

Cell typeMain jobMitochondria (approx. % of cell volume)
Heart muscle cellContracts nonstop, about 60 to 100 times a minute, for life30
Liver cellCarries out hundreds of chemical reactions20
Skeletal (leg) muscle cellContracts when the body moves5
Fat cellStores energy as fat2
Mature red blood cellCarries oxygen from the lungs to other cells0

As red blood cells in mammals mature, they lose their nucleus and their mitochondria. A mature red blood cell gets the small amount of energy it needs from a process that breaks down sugar without using oxygen.

Based on the passage, which is the best explanation for why it is an advantage for mature red blood cells to lack mitochondria?

Answer choices
Hint

Re-read what mitochondria use during cellular respiration, and what red blood cells carry. Then reason about what would happen if the two were combined.

Question 35 of 36

Dividing Cells in Normal and Tumor Tissue

Cancer is a disease in which cells divide without the controls that normally stop them. A pathologist stained two tissue samples from the same patient, one of normal skin and one of a skin tumor, and counted 500 cells in each. She recorded the stage of each cell.

The mitotic index is the percent of cells that are in one of the four stages of mitosis (prophase, metaphase, anaphase or telophase). Because the cells in a tissue are at different points in the cell cycle, the share of cells found in a stage reflects how much of the cycle that stage takes.

StageNormal skin (cells)Skin tumor (cells)
Interphase485410
Prophase850
Metaphase320
Anaphase210
Telophase210
Total500500

A drug stops dividing cells at metaphase: the cells cannot move on to anaphase. Cells that are already past metaphase finish dividing normally. If a piece of the skin tumor is treated with the drug for a few hours and the cells are counted again, which change in the counts is most likely?

Answer choices
Hint

Picture the cells moving through the stages like cars through a road with a roadblock at metaphase. Where do they pile up, and which stages after the roadblock empty out?

Question 36 of 36

Why Cells Stay Small

A class made cubes of agar, a firm gel, that contained an indicator dye. The dye turns pink when it meets a base. The students cut cubes that were 1 cm, 2 cm and 3 cm on each side. They placed all the cubes in the same dilute base solution for 10 minutes, then cut each cube in half. In every cube, the base had soaked in about 0.5 cm from each face. The students estimated what percent of each cube's volume had turned pink.

A cube's surface area is the total area of its six faces, and its volume is the space inside it. In a living cell, materials such as oxygen and nutrients enter through the surface (the cell membrane), but every part of the cell's volume needs them.

Side length (cm)Surface area (cm²)Volume (cm³)Surface area-to-volume ratioVolume turned pink (%)
1616 : 1100
22483 : 188
354272 : 170

An elephant's body is made of trillions of small cells rather than a smaller number of very large cells. Based on the passage, which statement best explains why?

Answer choices
Hint

Use the agar results as a model of a cell. What happens to the share of a cell that materials can reach as the cell gets bigger?